Tocolytics and preterm labour

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Prostaglandin endoperoxide H synthase inhibitors and other tocolytics in preterm labour.

Preterm delivery (<37 weeks of gestation) is the major obstetrical complication in developed countries, yet attempts to delay labour and prolong pregnancy have largely been unsuccessful. One of the many reasons it is so difficult to prevent preterm birth is that the nature of preterm labour changes as a function of gestational age, maternal lifestyle factors or infection, to list a few of the r...

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Administration of short-term tocolytic agents can prolong pregnancy for women in preterm labor. Prolonging pregnancy has many benefits because it allows for other proven interventions, such as antenatal corticosteroid administration, to be accomplished. This review provides an overview of currently utilized tocolytic agents and the evidence demonstrating their efficacy for prolonging pregnancy ...

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Management of preterm labour.

The above quote testifies to the complexity of preterm labour, a process that ultimately results in considerable neonatal morbidity and mortality. It is diYcult to quantify the incidence of spontaneous preterm labour, as many studies relating to preterm birth do not discriminate between spontaneous preterm labour and iatrogenic/therapeutic preterm delivery. The picture is further complicated as...

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ژورنال

عنوان ژورنال: BMJ

سال: 2009

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.b195